5-Amino-2-chloro-4-fluorophenol CAS 84478-72-8
| CAS No. | 84478-72-8 |
| Molecular Formula | C6H5ClFNO |
| Molecular Weight | 161.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-2-chloro-4-fluorophenol.
CATO supplies 5-Amino-2-chloro-4-fluorophenol (CAS 84478-72-8), a certified reference material (molecular formula C6H5ClFNO, MW 161.56 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 5-Amino-2-chloro-4-fluorophenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 161.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Amino-2-chloro-4-fluorophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFNO |
| Molecular Weight | 161.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 4-Amino-2-chloro-3-fluorophenol (CAS 1003710-18-6)
- 2-Amino-5-chloro-4-fluorophenol (CAS 1191063-34-9)
- 3-Amino-4-chloro-2-fluorophenol (CAS 1427407-07-5)
- 3-Amino-2-chloro-4-fluorophenol (CAS 1427407-23-5)
- 2-Amino-5-chloro-3-fluorophenol (CAS 186309-72-8)
- 2-Amino-4-chloro-5-fluorophenol (CAS 303181-72-8)
- 2-Amino-4-chloro-6-fluorophenol (CAS 862699-26-1)
- 2-Amino-6-chloro-4-fluorophenol (CAS 260253-17-6)
Recommended Standards
- 4-Amino-5-chloro-2-fluoro-phenol (CAS 847872-10-0)
- 5-Chloro-2-fluoro-3-(hydroxymethyl)pyridine (CAS 884494-79-5)
- 4-Amino-3-chloro-5-fluorophenol (CAS 847872-08-6)
- 5-Chloro-3-fluoro-2-hydrazinylpyridine (CAS 248255-70-1)
- 1-(2-Fluorophenyl)-3-methoxy-1H-pyrazole-5-carboxylic acid (CAS 1781899-13-5)
- 2-(4-Bromophenyl)-1H-imidazo[4,5-b]phenazine (CAS 114991-80-9)
- 3-[(3,5-dimethyl-4-nitro-1h-pyrazol-1-yl)methyl]-4-methoxybenzaldehyde (CAS 514800-77-2)
- 6-(Benzyloxy)-4-fluoro-1H-indazole (CAS 1253792-35-6)
- 3-(6-Phenylimidazo[2,1-b]thiazol-3-yl)-N-((tetrahydrofuran-2-yl)methyl)propanamide (CAS 1040671-74-6)
- Methyl 5-chloro-1-(2-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-09-9)
- tert-Butyl 4-(6,8-dichloro-2-(methylthio)pyrido[3,4-d]pyrimidin-4-yl)piperazine-1-carboxylate (CAS 2368910-58-9)
- 4-(4-Bromothiophen-2-yl)-2,6-dichloropyrimidine (CAS 1467839-29-7)
- 4-[(5-cyanopyridin-2-yl)oxy]benzoic acid (CAS 1093641-47-4)
- Semaglutide impurity 29 (CAS 1188328-22-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com