2-Chloro-6-iodoaniline CAS 84483-28-3
| CAS No. | 84483-28-3 |
| Molecular Formula | C6H5ClIN |
| Molecular Weight | 253.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 253.47 g/mol gives 2-Chloro-6-iodoaniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-6-iodoaniline (CAS 84483-28-3) is a high-purity analytical reference standard with the molecular formula C6H5ClIN and a molecular weight of 253.47 g/mol.
2-Chloro-6-iodoaniline (C6H5ClIN) contains a nitrile group, chlorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-6-iodoaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5ClIN |
| Molecular Weight | 253.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-5-iodo-2-methylpyridine (CAS 1092287-21-2)
- 2-Chloro-6-iodo-3-methylpyridine (CAS 1133961-30-4)
- 3-Chloro-2-iodo-4-methylpyridine (CAS 1188435-39-3)
- 2-Chloro-3-iodo-6-methylpyridine (CAS 1214372-51-6)
- 3-Chloro-6-iodo-2-methylpyridine (CAS 1227514-48-8)
- 4-Chloro-3-iodo-2-methylpyridine (CAS 1227515-08-3)
- 3-Chloro-4-iodo-2-methylpyridine (CAS 1227578-12-2)
- 2-Chloro-4-iodo-6-methylpyridine (CAS 1227592-89-3)
Recommended Standards
- 2-Chloro-5-iodo-4-methylpyridine (CAS 550347-54-1)
- 3-Chloro-2-iodoaniline (CAS 70237-25-1)
- 2-Chloro-5-iodo-3-methylpyridine (CAS 59782-89-7)
- 3-Chloro-5-iodoaniline (CAS 83171-49-7)
- 6-Methyl-2-(thiophen-3-yl)-1,3,6,2-dioxazaborocane-4,8-dione (CAS 1356166-65-8)
- 1-(2-Nitro-4-(trifluoromethyl)phenyl)propan-2-ol (CAS 1481569-39-4)
- 5-Hydroxy-2-nitropyridine (CAS 15206-26-5)
- 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-(3,5-difluorobenzyl)piperidine-4-carboxylic acid (CAS 916422-01-0)
- 3-(((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)(methyl)amino)-N-methylpropanamide (CAS 102128-83-6)
- (R)-Chroman-2-carbonitrile (CAS 850848-21-4)
- 2-Chloro-4-(difluoromethoxy)benzenethiol (CAS 1807213-34-8)
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- 3-(4-n-Propylphenyl)-1-propene (CAS 62826-25-9)
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