Raloxifene Impurity 21 CAS 84541-37-7
| CAS No. | 84541-37-7 |
| Molecular Formula | C29H29NO4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Raloxifene Impurity 21 (C29H29NO4SHCl) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Raloxifene Impurity 21 (CAS 84541-37-7), a pharmacopoeial impurity reference standard (molecular formula C29H29NO4SHCl, MW 524.07 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H29NO4S HCl |
| Molecular Weight | 524.07 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Raloxifene Standards
- Raloxifene Impurity 23 (CAS 102005-47-0)
- Raloxifene Impurity 19 (CAS 1100049-65-7)
- Raloxifene Impurity 18 (CAS 1100049-66-8)
- Raloxifene EP Impurity A (CAS 1159977-58-8)
- Raloxifene-d4 Bismethyl Ether (CAS 1185006-58-9)
- Raloxifene D4 (CAS 1185076-44-1)
- Raloxifene-d4 HCl (CAS 1188263-47-9)
- Raloxifene Impurity 4 (CAS 1191901-07-1)
Recommended Standards
- Bupivacaine Impurity 9 (CAS CATO-C4X-14829)
- Urapidil impurity 98 (CAS 91453-03-1（free base)）)
- Ilaprazole Impurity 41 (CAS CATO-C4X-113041)
- 2-(3-Fluorophenyl)-5-methyl-2h-1,2,3-triazole-4-carboxylic acid (CAS 1315368-15-0)
- methyl 7-bromo-4-fluoro-benzofuran-5-carboxylate (CAS 2306264-86-6)
- 4-Butanoyl-N-[(pyridin-3-yl)methyl]-1H-pyrrole-2-carboxamide (CAS 478259-70-0)
- 2-Methoxy-3-nitropyridine-4-carboxaldehyde (CAS 221349-76-4)
- BROMOPHENOL BLUE SODIUM SALT (CAS 62625-28-9)
- 2-(4-Methoxy-3-methylphenyl)pentan-2-ol (CAS 1443305-05-2)
- Semaglutide-d8 Tetratrifluoroacetate (CAS CATO-C4X-222617)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com