2-(Piperazin-1-yl)-5-(trifluoromethyl)pyrazine CAS 845618-10-2
| CAS No. | 845618-10-2 |
| Molecular Formula | C9H11F3N4 |
| Molecular Weight | 232.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Piperazin-1-yl)-5-(trifluoromethyl)pyrazine (CAS 845618-10-2), molecular formula C9H11F3N4 and molecular weight 232.21 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H11F3N4, 2-(Piperazin-1-yl)-5-(trifluoromethyl)pyrazine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 232.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Piperazin-1-yl)-5-(trifluoromethyl)pyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11F3N4 |
| Molecular Weight | 232.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Piperazin Standards
- 2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine (CAS 179756-91-3)
- 2-Piperazin-1-yl-5-(trifluoromethyl)pyrimidine (CAS 745066-18-6)
- 3-(Piperazin-1-yl)-5-(trifluoromethyl)pyridazine (CAS 845617-98-3)
- 3-(Piperazin-1-yl)-6-(trifluoromethyl)pyridazine (CAS 845618-11-3)
- 3-Ethyl-6-piperazin-1-yl[1,2,4]triazolo[4,3-b]pyridazine (CAS 1204296-47-8)
- 5-Ethyl-7-(piperazin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1774897-57-2)
- 2-phenyl-1-(piperazin-1-yl)butan-1-one (CAS 1016503-45-9)
- 4-Phenyl-1-(piperazin-1-yl)butan-1-one (CAS 137517-43-2)
Recommended Standards
- 2-(4-Fluorophenyl)pyrimidine-5-carboxylic Acid Methyl Ester (CAS 960198-50-9)
- 2-[(2-Fluorophenyl)amino]nicotinic acid (CAS 57978-54-8)
- 2-(4-Fluorophenyl)-4-methylpyrimidine-5-carboxylic acid (CAS 744261-56-1)
- 2-[(3-fluorophenyl)amino]pyridine-3-carboxylic acid (CAS 57978-55-9)
- 3-Bromo-1-trityl-1H-pyrazolo[4,3-b]pyridine (CAS 633328-34-4)
- Ethyl 1-(5-{[(3-fluoroanilino)carbonyl]amino}-2-pyridinyl)-3,5-dimethyl-1H-pyrazole-4-carboxylate (CAS 477712-83-7)
- 1,3-Bis(1,1-dimethylethyl) 2-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]imidodicarbonate (CAS 1391926-49-0)
- Sodium 1-benzylaziridine-2-carboxylate (CAS 114426-17-4)
- (S)-1-(2,6-Diisopropylphenyl)-3-(1-hydroxy-4-methylpentan-2-yl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate(V) (CAS 2067324-20-1)
- (1S,3R)-3-Amino-1-(Boc-amino)cyclohexane (CAS 1298101-47-9)
- (S)-tert-Butyl (1-(3-bromo-4-methoxyphenyl)ethyl)carbamate (CAS 701939-09-5)
- 3-(3,5-Dichlorophenyl)-1-(3-methylbutanoyl)imidazolidine-2,4-dione (CAS 70017-93-5)
- 2-[(E)-(4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)methylidene]-1-hydrazinecarbothioamide (CAS 583059-55-6)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com