2-Piperazin-1-yl-5-(trifluoromethyl)pyrimidine CAS 745066-18-6
| CAS No. | 745066-18-6 |
| Molecular Formula | C9H11F3N4 |
| Molecular Weight | 232.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Piperazin-1-yl-5-(trifluoromethyl)pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Piperazin-1-yl-5-(trifluoromethyl)pyrimidine (CAS 745066-18-6) is a high-purity analytical reference standard with the molecular formula C9H11F3N4 and a molecular weight of 232.21 g/mol.
2-Piperazin-1-yl-5-(trifluoromethyl)pyrimidine (C9H11F3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Piperazin-1-yl-5-(trifluoromethyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11F3N4 |
| Molecular Weight | 232.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Piperazin Standards
- 2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine (CAS 179756-91-3)
- 2-(Piperazin-1-yl)-5-(trifluoromethyl)pyrazine (CAS 845618-10-2)
- 3-(Piperazin-1-yl)-5-(trifluoromethyl)pyridazine (CAS 845617-98-3)
- 3-(Piperazin-1-yl)-6-(trifluoromethyl)pyridazine (CAS 845618-11-3)
- 3-Ethyl-6-piperazin-1-yl[1,2,4]triazolo[4,3-b]pyridazine (CAS 1204296-47-8)
- 5-Ethyl-7-(piperazin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1774897-57-2)
- 2-phenyl-1-(piperazin-1-yl)butan-1-one (CAS 1016503-45-9)
- 4-Phenyl-1-(piperazin-1-yl)butan-1-one (CAS 137517-43-2)
Recommended Standards
- 2-Nitrophenol-4-sulfomethylamide (CAS 96-58-2)
- 3-(5-(2-Fluorophenyl)furan-2-yl)acrylic acid (CAS 851398-31-7)
- 2-Methoxy-5-nitrobenzenesulfonamide (CAS 82020-46-0)
- 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (CAS 198474-05-4)
- N-Ethyl-3-fluoroaniline (CAS 2707-62-2)
- Ethyl 4-acetoxy-3-bromobenzoate (CAS 128401-55-8)
- Tert-butyl 4,4-dimethyl-1-oxa-6-azaspiro[2.5]Octane-6-carboxylate (CAS 1955531-11-9)
- Methyl 3-(Cyclopropylamino)-4-nitrobenzoate (CAS 1912589-06-0)
- 3-{4-methyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid (CAS 1235439-50-5)
- 5-(4-Chlorophenyl)-1-(p-tolyl)-N-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamide (CAS 477713-24-9)
- (3S)-Tryptophan EP Impurity I (Mixture of Diastereomers) (CAS 191279-37-5)
- 1-(Thiazol-5-ylmethyl)piperidin-4-ol (CAS 1261231-23-5)
- trans-4-tert-Butylcyclohexanol (CAS 21862-63-5)
- Insulin B (22-25) (CAS 34367-73-2)
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