Naphthol Yellow S Hydrate CAS 846-70-8
| CAS No. | 846-70-8 |
| Molecular Formula | C10H4N2O8S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Naphthol Yellow S Hydrate.
CATO supplies Naphthol Yellow S Hydrate (CAS 846-70-8), a certified reference material (molecular formula C10H4N2O8SNaH2O, MW 353.21 g/mol) for analytical method development and quality control.
Naphthol Yellow S Hydrate (C10H4N2O8SNaH2O) contains a carbohydrate-derived structure, an amide group, a sulfone group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Naphthol Yellow S Hydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H4N2O8S 2*Na H2O |
| Molecular Weight | 353.21 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Naphthol Standards
- Naphthol AS-GR phosphate disodium salt (CAS 100929-51-9)
- 4-Methyl-1-naphthol (CAS 10240-08-1)
- Naphthol AS Nonanoate (CAS 10523-82-7)
- 1-Methyl-2-naphthol (CAS 1076-26-2)
- 2-Naphthol-6,8-Disulfonic Acid (CAS 118-32-1)
- Naphthol AS-BI (CAS 1237-75-8)
- 1-Naphthol-D7 (CAS 124251-84-9)
- 1,1′-Di-2-naphthol bis(trifluoromethanesulfonate) (CAS 128575-34-8)
Recommended Standards
- Methyl 6-amino-5-nitronicotinate (CAS 104685-75-8)
- Isoxazolo[5,4-b]pyridine-3-acetonitrile (CAS 58035-53-3)
- 1-(methoxymethyl)cyclobutan-1-amine hydrochloride (CAS 1220039-33-7)
- (5-Butoxy-2-fluorophenyl)boronic acid (CAS 849062-31-3)
- 2-(2-Ethoxyphenyl)propan-1-amine (CAS 1096868-27-7)
- Etizolam Impurity 24 (CAS CATO-C4X-350924)
- N-(2-aminoethyl)piperidine-3-carboxamide (CAS 1215178-97-4)
- Voriconazole Impurity 22 (CAS CATO-C4X-136622)
- 4-Carbamoyl-1-methylpyridin-1-ium (CAS 45791-94-4)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
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