Dotarizine CAS 84625-59-2
| CAS No. | 84625-59-2 |
| Molecular Formula | C29H34N2O2 |
| Molecular Weight | 442.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Dotarizine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Dotarizine (CAS 84625-59-2), molecular formula C29H34N2O2 and molecular weight 442.59 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Dotarizine (C29H34N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C29H34N2O2 |
| Molecular Weight | 442.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 7,16-Dibenzyl-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane (CAS 69703-25-9)
- 50656-78-5 Nirtetralin Naphtho(2,3-d)-1,3-dioxole, 5-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydro-4-methoxy-6,7-bis(methoxymethyl)-, (5R,6S,7S)-rel- Naphtho(2,3-d)-1,3-dioxole, 5-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydro-4-methoxy-6,7-bis(methoxymethyl)-, (5alpha,6beta,7alpha)- (+-)-Nirtetralin (CAS 50656-78-5)
- 6,13-Di(thiophen-2-yl)pentacene (CAS 849466-79-1)
- Palonosetron Impurity 50 (CAS CATO-C4X-110550)
- N-(5-Bromo-4,6-dimethylpyrimidin-2-yl)thiophene-2-carboxamide (CAS 497060-01-2)
- (2E,4S)-4-Amino-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid Ethyl Ester (CAS 328086-61-9)
- 1,5-Dimethyl-1H-tetrazole (CAS 5144-11-6)
- 5-Bromo-3-chloro-2-pyridinecarboxylic Acid Methyl Ester (CAS 1214336-41-0)
- R406 (CAS 841290-81-1)
- 7-Bromo-N-methylquinolin-2-amine (CAS 959992-71-3)
- tert-Butyl 3-{[(benzyloxy)carbonyl]amino}azetidine-1-carboxylate (CAS 1017044-94-8)
- (S)-1-(6-Bromopyridin-3-yl)-2,2,2-trifluoro-N-methylethan-1-amine hydrochloride (CAS 2771010-43-4)
- 4-(Aminomethyl)phenyl acetate (CAS 75383-64-1)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com