5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine CAS 84737-35-9

Purity 97%+In StockPharmaceutical Standards
CAS No.84737-35-9
Molecular FormulaC6H3ClF4N2O
Molecular Weight230.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine CAS 84737-35-9 chemical structure

Description

The occurrence of 5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine (CAS 84737-35-9), molecular formula C6H3ClF4N2O and molecular weight 230.55 g/mol, is a CATO reference standard with documented purity and traceability.

5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine (C6H3ClF4N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H3ClF4N2O
Molecular Weight230.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1981
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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