N-Hydroxy-2H-chromene-3-carboxamidine CAS 84748-20-9

Purity 97%+In StockPharmaceutical Standards
CAS No.84748-20-9
Molecular FormulaC10H10N2O2
Molecular Weight190.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-Hydroxy-2H-chromene-3-carboxamidine CAS 84748-20-9 chemical structure

Description

The occurrence of N-Hydroxy-2H-chromene-3-carboxamidine is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-Hydroxy-2H-chromene-3-carboxamidine (CAS 84748-20-9), a certified reference material (molecular formula C10H10N2O2, MW 190.20 g/mol) for analytical method development and quality control.

The molecular framework of N-Hydroxy-2H-chromene-3-carboxamidine (C10H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-Hydroxy-2H-chromene-3-carboxamidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H10N2O2
Molecular Weight190.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1981
Nitrogen Atoms2

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