4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one CAS 847650-69-5
| CAS No. | 847650-69-5 |
| Molecular Formula | C10H14IN3O5 |
| Molecular Weight | 383.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one (CAS 847650-69-5), molecular formula C10H14IN3O5 and molecular weight 383.14 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one (C10H14IN3O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 383.14 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14IN3O5 |
| Molecular Weight | 383.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
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Recommended Standards
- 2,4-Difluorophenyl (2E)-3-(6-bromo-2H-1,3-benzodioxol-5-yl)prop-2-enoate (CAS 478259-08-4)
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- 3-(Benzyloxy)-4-iodo-5-nitrobenzaldehyde (CAS 1016976-13-8)
- 1-(2,4-dichlorophenyl)-4-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338773-18-5)
- Cropropamide (CAS 633-47-6)
- Ethyl 2-(3,5-dibromo-1h-1,2,4-triazol-1-yl)acetate (CAS 477869-80-0)
- 4-Amino-1-(trifluoromethyl)cyclohexane-1,3-diol (CAS 2770349-18-1)
- 3-Amino-4-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile (CAS 255909-26-3)
- 4-(3-Chlorophenyl)-1-(3-nitrophenyl)-1H-pyrazol-5-amine (CAS 324008-93-7)
- Benzyl 1,2-oxazepane-2-carboxylate (CAS 1217295-83-4)
- N-(2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclohexanecarboxamide (CAS 2575730-58-2)
- Ractopamine-d5 Hydrochloride (CAS CATO-LCAD300839-ME)
- (3R,5S)-1-(tert-Butoxycarbonyl)-5-(methoxycarbonyl)piperidine-3-carboxylic acid (CAS 534572-20-8)
- Bradykinin-Like Neuropeptide (Aplysia californica) (H-1654.0001) (CAS 165174-60-7)
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