methyl 4-amino-3-(benzyloxy)-5-iodobenzenecarboxylate CAS 1186405-03-7
| CAS No. | 1186405-03-7 |
| Molecular Formula | C15H14INO3 |
| Molecular Weight | 383.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of methyl 4-amino-3-(benzyloxy)-5-iodobenzenecarboxylate (C15H14INO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
methyl 4-amino-3-(benzyloxy)-5-iodobenzenecarboxylate (CAS 1186405-03-7) is a high-purity analytical reference standard with the molecular formula C15H14INO3 and a molecular weight of 383.18 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14INO3 |
| Molecular Weight | 383.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related methyl Standards
- 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(methylsulfinyl)-1H-pyrazole-3-carbonitrile (CAS 154807-27-9)
- 3-[[Amino[bis(2-chloroethyl)amino]phosphinyl]oxy]propanoic Acid Benzyl Ester 3-[[Amino[bis(2-chloroethyl)amino]phosphinyl]oxy]propanoic Acid Phenylmethyl Ester 37979-67-2 Carboxyphosphamide Benzyl Ester (CAS 37979-67-2)
- 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one (CAS 847650-69-5)
- 2-Amino-6-(4-bromophenyl)-4-phenyl-5,6-dihydro-1H-pyrrolo[3,4-d]pyrimidin-7(4H)-one (CAS 76628-96-1)
- 2-Amino-7-bromo-4-(thiophen-2-yl)-4H-benzo[g]chromene-3-carbonitrile (CAS 882747-32-2)
- Ethyl 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-((1,3-dioxoisoindolin-2-yl)methyl)-1H-1,2,3-triazole-4-carboxylate (CAS 311797-55-4)
- 6-Amino-1-phenyl-4-(pyridin-3-yl)-3-(trifluoromethyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 305868-30-8)
- 6-Amino-3-(tert-butyl)-4-(6-nitrobenzo[d][1,3]dioxol-5-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 5777-88-8)
Recommended Standards
- Glufosfamide,b-d-glucopyranose,1-(n,n-bis(2-chloroethyl)phosphorodiamidatE)- (CAS 132682-98-5)
- N-Iodoacetyl-β-(2-naphthyl)-alanine (CAS 1219437-29-2)
- 1206830-76-3 4-Methyl-5-tributylstannylpyridazine KS-000026AZ (CAS 1206830-76-3)
- 4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-((2-hydroxyethyl)(methyl)amino)pyridazin-3(2H)-one (CAS 338399-91-0)
- n-(1-Cyclopropylethyl)-3-methylaniline (CAS 1019587-50-8)
- (4-(Piperidin-4-ylmethoxy)phenyl)(pyrrolidin-1-yl)methanone (CAS 1306738-82-8)
- 2-Amino-2-methylbutan-1-ol Oxalate (CAS 22435-95-6)
- Agomelatine Impurity 4 (CAS CATO-C4X-11084)
- Ceritinib Impurity 62 (CAS CATO-C4X-104862)
- 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose (CAS 7772-79-4)
- 3,5-Pyridinedicarbonyl dichloride, 2-(difluoromethyl)-4-(2-methylpropyl)-6-(trifluoromethyl)- (CAS 97898-34-5)
- 1-Methoxy-4-(2-methylprop-1-en-1-yl)benzene (CAS 877-99-6)
- (S)-3-Methyl-2-butylamine Hydrochloride (CAS 31519-53-6)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com