1-Benzhydryl-3-(trifluoromethyl)-3-azetidinol CAS 848192-92-7

Description

The occurrence of 1-Benzhydryl-3-(trifluoromethyl)-3-azetidinol is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-Benzhydryl-3-(trifluoromethyl)-3-azetidinol (CAS 848192-92-7), molecular formula C17H16F3NO and molecular weight 307.31 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-Benzhydryl-3-(trifluoromethyl)-3-azetidinol (C17H16F3NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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