1-Phenyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine CAS 385404-01-3
| CAS No. | 385404-01-3 |
| Molecular Formula | C16H16F3N3 |
| Molecular Weight | 307.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Phenyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-Phenyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine (CAS 385404-01-3), a certified reference material (molecular formula C16H16F3N3, MW 307.31 g/mol) for analytical method development and quality control.
Structurally, 1-Phenyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine (C16H16F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 307.31 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Phenyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16F3N3 |
| Molecular Weight | 307.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 1-Benzhydryl-3-(trifluoromethyl)-3-azetidinol (CAS 848192-92-7)
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- 15-Bromopentadecan-1-ol (CAS 59101-27-8)
- 2-((1H-Benzo[d][1,2,3]triazol-1-yl)methyl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole (CAS 306990-71-6)
- 7-((1-Butyl-2,5-dioxopyrrolidin-3-yl)thio)heptyl acetate (CAS 62164-04-9)
- 5-Fluoro-1-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 77180-80-4)
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- 1-(Oxetan-3-yl)cyclopropan-1-amine hydrochloride (CAS 2306270-54-0)
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- 1-(4-Nitro-1H-pyrazol-5-yl)ethanone (CAS 2228374-35-2)
- (R)-3,3'-Bis[4-tert-butylphenyl]-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol (CAS 1205537-80-9)
- 2-(3-chloropropyl)-1,3,4-oxadiaZole (CAS 1250961-59-1)
- Tetrakis(acetamidato)dirhodium (CAS 87985-40-8)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
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