5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride CAS 848422-44-6
| CAS No. | 848422-44-6 |
| Molecular Formula | C14H6ClF4N3O |
| Molecular Weight | 343.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (CAS 848422-44-6), molecular formula C14H6ClF4N3O and molecular weight 343.66 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (C14H6ClF4N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 343.66 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H6ClF4N3O |
| Molecular Weight | 343.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- (3-(4-Fluorophenyl)azepan-1-yl)(2-(methylthio)phenyl)methanone (CAS 1797545-94-8)
- 2-((4-Fluorophenyl)thio)-1-(4-methyl-2-phenylthiazol-5-yl)ethan-1-one (CAS 478047-47-1)
- 2-(4-Fluorophenyl)-N-(2-(1-methyl-4-(thiophen-2-yl)-1H-imidazol-2-yl)ethyl)acetamide (CAS 1396764-96-7)
- 3-(2-Fluorophenyl)-N-(furan-2-ylmethyl)-N-(thiophen-3-ylmethyl)propanamide (CAS 1797074-14-6)
- 3-(2-Fluorophenyl)-N-(furan-3-ylmethyl)-N-(thiophen-2-ylmethyl)propanamide (CAS 1797214-33-5)
- (2Z)-2-[(2-Fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-yl thiophene-2-carboxylate (CAS 477871-49-1)
- N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)propionamide (CAS 897618-38-1)
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Recommended Standards
- 2-((4-Chlorobenzyl)amino)-N-(2,3-dichlorophenyl)acetamide (CAS 303091-23-8)
- Bromoheptadecylmagnesium (CAS 1227752-33-1)
- 1-(4-Chloropyridin-2-yl)-2,2,2-trifluoroethyl trifluoromethanesulfonate (CAS 1356087-54-1)
- (3-(Benzyloxy)-6-bromo-2-chlorophenyl)(methyl)sulfane (CAS 2379321-45-4)
- 4h,5h,6h,7h-Thieno[3,2-c]pyridine-4-carboxylic acid hydrochloride (CAS 1251924-21-6)
- 2-(2-Bromophenoxy)ethane-1-sulfonyl chloride (CAS 1018289-19-4)
- Bicyclo[2.2.1]Heptane-2-carbohydrazide (CAS 1016557-67-7)
- 3-(Difluoromethyl)-4-(2-methoxyethoxy)aniline (CAS 1341103-02-3)
- Erlotinib Impurity 56 (CAS CATO-C4X-106956)
- 1-(2-Fluorobenzyl)-1h-imidazole-5-carboxylic acid (CAS 1439897-71-8)
- (4-(Trifluoromethyl)phenethyl)hydrazine (CAS 1249389-24-9)
- 5-Chloro-6-methyl-2H-indazole (CAS 1000343-64-5)
- 3-(4-Mesityl-5-methylthiazol-2-yl)aniline (CAS 1416338-74-3)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
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