5-(3,4-Dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 848436-25-9
| CAS No. | 848436-25-9 |
| Molecular Formula | C16H12F3N3O2 |
| Molecular Weight | 335.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-(3,4-Dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C16H12F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 335.28 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(3,4-Dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 848436-25-9) is a high-purity analytical reference standard with the molecular formula C16H12F3N3O2 and a molecular weight of 335.28 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(3,4-Dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12F3N3O2 |
| Molecular Weight | 335.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dimethylphenyl Standards
- N-(3,5-Dimethylphenyl)-2-((2-ethylquinazolin-4-yl)oxy)acetamide (CAS 1115871-35-6)
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Recommended Standards
- 4-(((4-(Trifluoromethoxy)phenyl)amino)methyl)phthalazin-1(2H)-one (CAS 305368-11-0)
- 5-(4-Ethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 678543-10-7)
- 2-{2-[3-(trifluoromethyl)phenoxy]ethyl}-2,3-dihydro-1H-isoindole-1,3-dione (CAS 321432-39-7)
- 5-[(1Z)-1-(Dimethylamino)-4,4,4-trifluoro-3-oxobut-1-en-2-yl]-3-phenyl-1,2-oxazole-4-carbonitrile (CAS 339106-85-3)
- 2-(4-Formyl-2-iodo-6-methoxyphenoxy)-N-(2-methoxyphenyl)acetamide (CAS 692276-01-0)
- 3-(2,5-Difluorophenyl)piperidine (CAS 1044768-90-2)
- 1-hexyl-3-methylimidazolium iodide (CAS 178631-05-5)
- Dimethyl 3-amino-4,5-dimethylphthalate (CAS 2828444-24-0)
- (5-Chlorothiophen-2-yl)(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone (CAS 1788681-94-6)
- 5-(4-Methoxyphenyl)thiophene-2-carbohydrazide (CAS 69202-24-0)
- Cinitapride Impurity 14 (CAS CATO-C4X-290814)
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