Bedaquiline impurity 40 CAS 848694-09-7
| CAS No. | 848694-09-7 |
| Molecular Formula | C9H11Cl2NO |
| Molecular Weight | 220.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Bedaquiline impurity 40 (CAS 848694-09-7, C9H11Cl2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Bedaquiline impurity 40 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Bedaquiline impurity 40 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11Cl2NO |
| Molecular Weight | 220.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bedaquiline Standards
- Bedaquiline Impurity 67 (CAS 345949-37-3)
- Bedaquiline impurity 41 (CAS 860720-24-7)
- Bedaquiline impurity 42 (CAS 90279-39-3)
- Bedaquiline Impurity 16 (CAS CATO-C4X-116716)
- Bedaquiline Impurity 17 (CAS CATO-C4X-116717)
- Bedaquiline Impurity 7 (CAS 2752-87-6)
- Bedaquiline Impurity 68 (CAS 110486-69-6)
- Bedaquiline Impurity 9 (CAS 22422-69-1)
Recommended Standards
- rel-(3aR,6aS)-2-(p-Tolyl)tetrahydrothieno[3,4-d][1,3,2]dioxaborole (CAS 62729-35-5)
- 4-bromo-1-methyl-1H-pyrazolo[3,4-c]pyridine (CAS 1032943-41-1)
- N-Butyl-3,6-dichloropyridazin-4-amine (CAS 61261-40-3)
- 1-(5-bromo-2-pyridyl)propan-1-one (CAS 1060812-89-6)
- Menaquinone impurity 19 (CAS 65061-22-5)
- Lusutrombopag Impurity 42 (CAS 1367365-00-1)
- Estazolam Impurity 10 (CAS 112393-62-1)
- (E)-3-(dimethylamino)-N-phenylacrylamide (CAS 344554-55-8)
- 2-(3-Methoxyphenyl)-2-oxoethyl (2E,4E)-hexa-2,4-dienoate (CAS 859137-70-5)
- Ethyl 5-Methyl-4-oxazolecarboxylate (CAS 32968-44-8)
- Ergovaline (CAS 2873-38-3)
- 2-(1H-Pyrazolo[5,1-c][1,2,4]triazol-3-yl)ethanamine (CAS 197355-88-7)
- 1-Fluoro-3-oxocyclobutane-1-carbonitrile (CAS 2231677-14-6)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com