Lusutrombopag Impurity 42 CAS 1367365-00-1
| CAS No. | 1367365-00-1 |
| Molecular Formula | C8H4Cl2O3 |
| Molecular Weight | 219.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Lusutrombopag Impurity 42 (CAS 1367365-00-1), a pharmacopoeial impurity reference standard (molecular formula C8H4Cl2O3, MW 219.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Lusutrombopag Impurity 42 (C8H4Cl2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Lusutrombopag Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2O3 |
| Molecular Weight | 219.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 44 (CAS 2126856-49-1)
- Lusutrombopag Impurity 73 (CAS CATO-C4X-208473)
- Lusutrombopag Impurity 74 (CAS CATO-C4X-208474)
- Lusutrombopag Impurity 75 (CAS CATO-C4X-208475)
- Lusutrombopag Impurity 76 (CAS CATO-C4X-208476)
- Lusutrombopag Impurity N2 (CAS 89894-53-1)
- Lusutrombopag Impurity 4 (CAS CATO-C4X-20844)
- Lusutrombopag Impurity N5 (CAS 29841-69-8)
Recommended Standards
- 2-iodanyl-3-methyl-pyridine 2-iodo-3-methylpyridine 22282-58-2 A816084 (CAS 22282-58-2)
- 6-Chloro-3-(chloromethyl)oxazolo[4,5-b]pyridin-2(3H)-one (CAS 35570-70-8)
- 5-Iodo-2-methylpyridine (CAS 695-17-0)
- 5-(1-Cyanocyclobutyl)-2-fluorophenylboronic acid (CAS 2096339-45-4)
- Argatroban Impurity 62 (CAS CATO-C4X-100762)
- Choline impurity 4 (CAS CATO-C4X-15874)
- Imatinib Impurity 76 (CAS CATO-C4X-106876)
- 3-(Furan-3-yl)-1-methyl-4-propyl-1h-pyrazol-5-amine (CAS 1522916-35-3)
- Proheptazine Hydrochloride(Mixture of Diastereomers) (CAS 856575-01-4)
- 4-(Tert-butylamino)furan-2(5H)-one (CAS 54494-75-6)
- 5-Ethynylnicotinonitrile (CAS 152803-05-9)
- 2-(Cyclopropylethynyl)thiazole (CAS 329204-45-7)
- 5-Bromo-3-(difluoromethyl)-4-methylpyridin-2-amine (CAS 1806801-94-4)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com