2-(Chloromethyl)nicotinonitrile CAS 848774-96-9
| CAS No. | 848774-96-9 |
| Molecular Formula | C7H5ClN2 |
| Molecular Weight | 152.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(Chloromethyl)nicotinonitrile (CAS 848774-96-9), molecular formula C7H5ClN2 and molecular weight 152.58 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Chloromethyl)nicotinonitrile (C7H5ClN2) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2-(Chloromethyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2 |
| Molecular Weight | 152.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 5-(Chloromethyl)picolinonitrile (CAS 105954-37-8)
- 4-(Chloromethyl)nicotinonitrile (CAS 1060802-60-9)
- 6-(Chloromethyl)-2-cyanopyridine (CAS 135450-23-6)
- 2-(Chloromethyl)isonicotinonitrile (CAS 51454-64-9)
- 3-(Chloromethyl)isonicotinonitrile (CAS 58553-52-9)
- 3-(Chloromethyl)picolinonitrile (CAS 205984-76-5)
- 4-(Chloromethyl)pyridine-2-carbonitrile (CAS 71935-33-6)
- 2-(chloromethyl)-5-fluoropyrimidine (CAS 1196151-61-7)
Recommended Standards
- 2-Amino-3-chlorobenzonitrile (CAS 53312-77-9)
- 2-(5-Chloropyridin-3-yl)acetonitrile (CAS 39891-07-1)
- 2-Chloro-3-hydroxypentanoic acid (CAS 250261-42-8)
- 2-(3-Chloro-4-pyridyl)acetonitrile (CAS 485828-87-3)
- 5,6-Diamino-1H-pyrimidin-2-one (CAS 23899-73-2)
- 4-(3-Methoxy Phenyl)-Imidazole (CAS 53848-01-4)
- Ethyl 2-(4-hydroxy-1,1-dioxidotetrahydro-2h-thiopyran-4-yl)acetate (CAS 1249576-10-0)
- 2-(2-(2,4-Dinitrophenyl)hydrazine-1-carbonyl)benzoic acid (CAS 95980-68-0)
- 1-Methyl-4-(nitromethyl)cyclohexan-1-ol (CAS 1935646-23-3)
- Thiotepa Impurity 12 (CAS 2835499-20-0)
- N-(4-Fluorobenzyl)cyanamide (CAS 1255147-62-6)
- 2,2-Difluorobutan-1-ol (CAS 784193-12-0)
- 4-[(4-chlorophenyl)methylidene]-1,2,3,4-tetrahydroacridine-9-carboxylic acid (CAS 379728-21-9)
- Allo-D-Ile27-Tirzepatide (CAS CATO-CPTD788961)
Why CATO?
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