Ethyl 2-(4-Fluoro-3-indolyl)-2-oxoacetate CAS 849630-89-3
| CAS No. | 849630-89-3 |
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 2-(4-Fluoro-3-indolyl)-2-oxoacetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ethyl 2-(4-Fluoro-3-indolyl)-2-oxoacetate (CAS 849630-89-3) is a high-purity analytical reference standard with the molecular formula C12H10FNO3 and a molecular weight of 235.21 g/mol.
The molecular framework of Ethyl 2-(4-Fluoro-3-indolyl)-2-oxoacetate (C12H10FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- Ethyl 2-(3-fluorophenyl)oxazole-4-carboxylate (CAS 885272-98-0)
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- 5-(((Furan-2-ylmethyl)amino)methyl)-1,3-dimethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 878453-02-2)
- Methyl 2-chloro-4-methyl-3-oxo-2,3-dihydrothiophene-2-carboxylate (CAS 128775-88-2)
- 2-(Dimethylamino)-4-((4-methoxyphenyl)amino)-6-oxo-6H-1,3-oxazine-5-carbonitrile (CAS 303997-21-9)
- tert-Butyl 4-methylindoline-1-carboxylate (CAS 1824265-66-8)
- 2-Cyclopropoxy-4-fluoro-N-methylbenzamide (CAS 1243463-80-0)
- N-ethyl 2-bromo-4-pyridinecarboxamide (CAS 951885-78-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com