4,6-Difluoropicolinic acid CAS 849937-89-9
| CAS No. | 849937-89-9 |
| Molecular Formula | C6H3F2NO2 |
| Molecular Weight | 159.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,6-Difluoropicolinic acid.
4,6-Difluoropicolinic acid (CAS 849937-89-9) is a high-purity analytical reference standard with the molecular formula C6H3F2NO2 and a molecular weight of 159.09 g/mol.
4,6-Difluoropicolinic acid (C6H3F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4,6-Difluoropicolinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3F2NO2 |
| Molecular Weight | 159.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoropicolinic Standards
Recommended Standards
- 4,6-Difluoronicotinic Acid (CAS 849937-91-3)
- 3,6-Difluoro pyridine-2-carboxylic acid 3,6-Difluoro-2-pyridinecarboxylic acid;3,6-difluoropicolinic acid 851386-45-3 A26073 (CAS 851386-45-3)
- 3,5-Difluoropyridine-2-carboxylic Acid (CAS 745784-04-7)
- 2,3-Difluoronitrobenzene (CAS 6921-22-8)
- 2-Cyclopropylbenzonitrile (CAS 3154-99-2)
- 3-Fluorothiophene-2-carbohydrazide (CAS 258522-49-5)
- 1-(2,4-Dihydroxyphenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one (CAS 26962-50-5)
- N-(2-methoxyphenyl)nicotinamide (CAS 70301-27-8)
- 2-((3-Amino-1,1,1-trifluoropropan-2-yl)oxy)acetic acid (CAS 1354950-44-9)
- 4,4,5,5-Tetramethyl-2-[5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-yl]-1,3,2-dioxaborolane (CAS 2377607-50-4)
- 4-[(N,2-dimethylpropanamido)methyl]benzoic acid (CAS 1183845-86-4)
- 4-Hydroxy-1H-pyrazol-3(2H)-one (CAS 53666-86-7)
- 2-(Cyclopentylthio)-1,5-diphenyl-1H-imidazole (CAS 1207011-67-3)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com