5-(4-Chlorobenzyl)thiazolidine-2,4-dione CAS 85002-48-8
| CAS No. | 85002-48-8 |
| Molecular Formula | C10H8ClNO2S |
| Molecular Weight | 241.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5-(4-Chlorobenzyl)thiazolidine-2,4-dione (CAS 85002-48-8), a certified reference material (molecular formula C10H8ClNO2S, MW 241.69 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-Chlorobenzyl)thiazolidine-2,4-dione (C10H8ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO2S |
| Molecular Weight | 241.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
- 3-(4-Chlorobenzyl)-1,3-thiazolidine-2,4-dione (CAS 103027-70-9)
- 3-(2-Chlorobenzyl)-1,3-thiazolidine-2,4-dione (CAS 56347-37-6)
- Methyl 4-((4-chlorobenzyl)amino)butanoate (CAS 1096805-24-1)
- Methyl 4-((2-chlorobenzyl)amino)butanoate (CAS 1096859-39-0)
- Methyl 2-((4-chlorobenzyl)amino)-2-methylpropanoate (CAS 1157807-51-6)
- 2-((2-Chlorobenzyl)(isopropyl)amino)acetic acid (CAS 1178365-59-7)
- 2-((4-Chlorobenzyl)(isopropyl)amino)acetic acid (CAS 1181654-06-7)
- 2-((3-Chlorobenzyl)(isopropyl)amino)acetic acid (CAS 1181697-60-8)
Recommended Standards
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- 7-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione (CAS 321-50-6)
- 2-(Benzylamino)-N-(4-ethoxyphenyl)-2-thioxoacetamide (CAS 329078-52-6)
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