4-methyl-3-nitrobenzene-1-sulfonyl chloride CAS 616-83-1
| CAS No. | 616-83-1 |
| Molecular Formula | C7H12ClNO4S |
| Molecular Weight | 241.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-methyl-3-nitrobenzene-1-sulfonyl chloride (CAS 616-83-1), molecular formula C7H12ClNO4S and molecular weight 241.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-methyl-3-nitrobenzene-1-sulfonyl chloride (C7H12ClNO4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-methyl-3-nitrobenzene-1-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H12ClNO4S |
| Molecular Weight | 241.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related methyl Standards
- 5-Methyl-2-nitrobenzene-1-sulfonyl chloride (CAS 173908-60-6)
- 4-Ethyl-3-nitrobenzene-1-sulfonyl chloride (CAS 495416-81-4)
- 1-[(4-nitrobenzene)sulfonyl]imidazole (CAS 110349-30-9)
- 2-[(4-nitrobenzene)sulfinyl]acetic acid (CAS 3406-71-1)
- 5-Nitrobenzene-1,2,3-tricarboxylic acid (CAS 3807-81-6)
- 2-Nitrobenzene-1-sulfonyl Azide (CAS 6655-31-8)
- 2-ethyl-5-nitrobenzene-1-sulfonyl chloride (CAS 89189-34-4)
- 1-Butyl-3-nitrobenzene (CAS 20651-76-7)
Recommended Standards
- 4-Chloronaphthalene-1-sulfonamide (CAS 6292-61-1)
- 5-(((4-Chlorophenyl)thio)methyl)isoxazol-3(2H)-one (CAS 89660-84-4)
- 4-Chloro-7-(methylsulfonyl)quinoline (CAS 49713-63-5)
- 5-(4-Chlorobenzyl)thiazolidine-2,4-dione (CAS 85002-48-8)
- 4-(2,2-Difluoroethyl)piperidine-4-carboxylic acid (CAS 1503725-95-8)
- 5,6-Diamino-2-methoxy-3-methylpyrimidin-4(3H)-one (CAS 85357-27-3)
- 2-(Chloromethyl)dibenzo[b,d]furan (CAS 77358-96-4)
- Methyl 6-(4-formylpiperazin-1-yl)nicotinate (CAS 1355230-90-8)
- 2-Chloro-5-(trifluoromethyl)quinoline (CAS 886761-95-1)
- 5-Bromo-2-fluorothiazole (CAS 1207608-60-3)
- 4-Chloro-1-((tetrahydro-2h-pyran-2-yl)methyl)-1h-pyrazol-3-amine (CAS 1409512-74-8)
- 4-[2-(3-Phenylpropoxy)ethyl]piperidine (CAS 907159-15-3)
- 4-(3,4-Dichlorophenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (CAS 862658-93-3)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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