2,4-Difluoro-N-(4-(methylsulfonyl)phenyl)benzamide CAS 850149-96-1
| CAS No. | 850149-96-1 |
| Molecular Formula | C14H11F2NO3S |
| Molecular Weight | 311.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,4-Difluoro-N-(4-(methylsulfonyl)phenyl)benzamide (C14H11F2NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2,4-Difluoro-N-(4-(methylsulfonyl)phenyl)benzamide (CAS 850149-96-1), molecular formula C14H11F2NO3S and molecular weight 311.30 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11F2NO3S |
| Molecular Weight | 311.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 5-(Pyridin-2-yl)pentan-2-one (CAS 90874-87-6)
- (s)-2-Amino-2-(4-fluoro-3-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1213413-72-9)
- Methyl 3-(4-bromo-1h-pyrazol-1-yl)-2-methyl-2-(methylamino)propanoate (CAS 1249617-08-0)
- 4-Chloro-1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole (CAS 2818961-90-7)
- 2,5-diaminoanisole Sulfate (CAS 66671-82-7)
- 2-Amino-3-(6-amino-9H-purin-9-yl)propanoic acid (CAS 22892-24-6)
- 2-[(5,7-dichloro-2-methylquinolin-8-yl)oxy]acetohydrazide (CAS 730949-87-8)
- 4-n-Butyl-2-iodobenzophenone (CAS 64358-27-6)
- 2-hydroxypropyl (2-isopropyl-5-methylcyclohexyl) carbonate (CAS CATO-C3D-262377)
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