5-Bromo-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole CAS 850375-27-8

Purity 97%+In StockPharmaceutical Standards
CAS No.850375-27-8
Molecular FormulaC11H7BrF3NS
Molecular Weight322.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole CAS 850375-27-8 chemical structure

Description

5-Bromo-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 850375-27-8) is a high-purity analytical reference standard with the molecular formula C11H7BrF3NS and a molecular weight of 322.14 g/mol.

The molecular framework of 5-Bromo-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole (C11H7BrF3NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Bromo-4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H7BrF3NS
Molecular Weight322.14 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Br-containing
Nitrogen Atoms1
Sulfur Atoms1

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