(2,5-Difluorophenyl)methanamine CAS 85118-06-5
| CAS No. | 85118-06-5 |
| Molecular Formula | C7H7F2N |
| Molecular Weight | 143.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 143.13 g/mol gives (2,5-Difluorophenyl)methanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2,5-Difluorophenyl)methanamine (CAS 85118-06-5) is a high-purity analytical reference standard with the molecular formula C7H7F2N and a molecular weight of 143.13 g/mol.
Owing to a nitrile group, fluorine substitution, an aromatic ring system, (2,5-Difluorophenyl)methanamine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2,5-Difluorophenyl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7F2N |
| Molecular Weight | 143.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
- (2,3-Difluorophenyl)methanamine (CAS 72235-51-9)
- (3,5-Difluorophenyl)methanamine hydrochloride (CAS 90389-28-9)
- (3,5-Difluorophenyl)hydrazine (CAS 134993-88-7)
- (3,4-Difluorophenyl)hydrazine (CAS 161886-22-2)
- (2,4-difluorophenyl)hydrazine (CAS 40594-30-7)
- (2,4-Difluorophenyl)methanol (CAS 56456-47-4)
- (2,5-Difluorophenyl)methanol (CAS 75853-20-2)
- O-(3,5-difluorophenyl)hydroxylamine (CAS 197588-25-3)
Recommended Standards
- 2,3-Difluoro-6-methylaniline (CAS 1807099-38-2)
- 2,3-Difluoro-4-methylaniline (CAS 886503-79-3)
- 4-(Difluoromethyl)-2-methylpyridine (CAS 1805310-42-2)
- 2,3-Difluoro-N-methylaniline (CAS 470458-54-9)
- 1-(Pyrrolidine-1-sulfonyl)piperazine (CAS 923681-40-7)
- 4-(2-Ethynylcyclopropyl)benzonitrile (CAS 2735014-82-9)
- (5,6-Dichloropyridin-3-yl)methanamine (CAS 1256794-26-9)
- (1H-Pyrrolo[3,2-b]pyridin-2-yl)methanamine (CAS 1245808-67-6)
- n-((5-Bromothiophen-2-yl)methyl)-4-methylpyridin-3-amine (CAS 1342837-04-0)
- 4-Iodo-2',5'-dimethyl-2'h-[1,3'-bipyrazole]-4'-carbaldehyde (CAS 1340096-28-7)
- 2-(5-Chloro-2-hydroxyphenyl)-4-methyl-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione (CAS 342422-08-6)
- Hydroxychloroquine Impurity 12 (CAS CATO-C4X-183512)
- Ethyl 7-hydroxybenzo[b]thiophene-2-carboxylate (CAS 1956371-74-6)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
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