Pyrimidin-2-ylboronic acid CAS 851199-85-4

Purity 97%+In StockPharmaceutical Standards
CAS No.851199-85-4
Molecular FormulaC4H5BN2O2
Molecular Weight123.91 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Pyrimidin-2-ylboronic acid CAS 851199-85-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 123.91 g/mol gives Pyrimidin-2-ylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Pyrimidin-2-ylboronic acid (CAS 851199-85-4), molecular formula C4H5BN2O2 and molecular weight 123.91 g/mol, is a CATO reference standard with documented purity and traceability.

Pyrimidin-2-ylboronic acid (C4H5BN2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H5BN2O2
Molecular Weight123.91 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Nitrogen Atoms2

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