Rosuvastatin Impurity 42 CAS 851443-04-4
| CAS No. | 851443-04-4 |
| Molecular Formula | C24H32FN3O6S |
| Molecular Weight | 509.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Rosuvastatin Impurity 42 (CAS 851443-04-4) is a certified pharmaceutical impurity reference standard with the molecular formula C24H32FN3O6S and a molecular weight of 509.59 g/mol.
Rosuvastatin Impurity 42 (C24H32FN3O6S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Rosuvastatin Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H32FN3O6S |
| Molecular Weight | 509.59 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 212 (CAS CATO-C4X-1169212)
- Rosuvastatin Impurity 213 (CAS CATO-C4X-1169213)
- Rosuvastatin 3-Oxo Acid Ethyl Ester (CAS 901765-36-4)
- Rosuvastatin-d3 Sodium Salt (CAS 1279031-70-7)
- Rosuvastatin Impurity 158 (CAS CATO-C4X-1169158)
- Rosuvastatin Impurity 142 (CAS CATO-C4X-1169142)
- Rosuvastatin Impurity 143 (CAS CATO-C4X-1169143)
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- 2-(2-Methyloxazol-5-yl)acetonitrile (CAS 1159511-94-0)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com