Rosuvastatin Impurity 158 CAS CATO-C4X-1169158
| CAS No. | CATO-C4X-1169158 |
| Molecular Formula | C22H29FN3NaO6S |
| Molecular Weight | 505.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rosuvastatin Impurity 158 (CAS CATO-C4X-1169158) is a certified pharmaceutical impurity reference standard with the molecular formula C22H29FN3NaO6S and a molecular weight of 505.54 g/mol.
The molecular framework of Rosuvastatin Impurity 158 (C22H29FN3NaO6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H29FN3NaO6S |
| Molecular Weight | 505.54 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin-d3 Sodium Salt (CAS 1279031-70-7)
- Rosuvastatin 3-Oxo Acid Ethyl Ester (CAS 901765-36-4)
- Rosuvastatin Impurity 212 (CAS CATO-C4X-1169212)
- Rosuvastatin Impurity 213 (CAS CATO-C4X-1169213)
- Rosuvastatin Impurity 42 (CAS 851443-04-4)
- Rosuvastatin Impurity 135 (CAS CATO-C4X-1169135)
- Rosuvastatin Impurity 200 (CAS CATO-C4X-1169200)
- Rosuvastatin Impurity 201 (CAS CATO-C4X-1169201)
Recommended Standards
- N-Bn-Moxifloxacin Impurity (CAS CATO-C4X-1074115)
- Adavivint (CAS 1467093-03-3)
- Methyl 3-(3-carbamoyl-4-(3-methoxyphenylamino)-8-methylquinolin-6-ylsulfonyl)benzoate (CAS 801311-24-0)
- (E)-[(5-{[(4-tert-butylphenyl)methyl]sulfanyl}-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylidene]amino 4-methoxybenzoate (CAS 318239-32-6)
- Cinacalcet Impurity N86 (CAS 129254-76-8)
- Posaconazole Impurity 164 (CAS CATO-C4X-1208164)
- Crizotinib Impurity 52 (CAS CATO-C4X-102552)
- 4-(3-Chlorophenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-5-amine (CAS 242797-30-4)
- 3-Bromo-2,4-dichloro-8-fluoroquinoline (CAS 1447959-10-5)
- 4-[(4-Chlorobenzyl)amino]benzohydrazide (CAS 439093-68-2)
- (Z)-2-(tert-Butyl)-4-(2-methoxybenzylidene)oxazol-5(4H)-one (CAS 1322262-39-4)
- (4S,4'S)-2,2'-(2-(4-(tert-Butyl)phenyl)ethane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) (CAS 2634687-80-0)
- GRK2i (CAS 148505-03-7)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com