4-(2-Chlorophenyl)piperazine-1-carboximidamide hydroiodide CAS 852228-16-1
| CAS No. | 852228-16-1 |
| Molecular Formula | C11H15ClN4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2-Chlorophenyl)piperazine-1-carboximidamide hydroiodide is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(2-Chlorophenyl)piperazine-1-carboximidamide hydroiodide (CAS 852228-16-1), molecular formula C11H15ClN4HI and molecular weight 366.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(2-Chlorophenyl)piperazine-1-carboximidamide hydroiodide (C11H15ClN4HI) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15ClN4 HI |
| Molecular Weight | 366.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 4 |
Related Chlorophenyl Standards
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- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
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- 1-(2-Chlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000577-29-6)
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Recommended Standards
- N-(1-benzylpiperidin-4-yl)-4-(tert-butyl)benzamide (CAS 334974-41-3)
- 5-(2-Nitrophenyl)isoxazole-3-carboxylic Acid (CAS 1232028-11-3)
- 2,3,3-Triphenylacrylonitrile (CAS 6304-33-2)
- 1-Bromo-2-(1-bromopropan-2-yl)benzene (CAS 1489124-59-5)
- methyl trans-6-methylpiperidine-3-carboxylate hydrochloride (CAS 1009376-86-6)
- (E)-2',3',9',10'-tetrahydrospiro[cyclohexane-1,8'-cyclopenta[c]pyrano[3,2-g]chromen]-4'(1'H)-one oxime (CAS 929841-66-7)
- Azelastine impurity 66 (CAS CATO-C4X-139666)
- Fudosteine Impurity 24 (CAS CATO-C4X-144724)
- 5-(Difluoromethyl)-3-propyl-1h-1,2,4-triazole (CAS 1248604-96-7)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
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