2-(1-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]Decan-3-yl)acetic acid CAS 852400-33-0
| CAS No. | 852400-33-0 |
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(1-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]Decan-3-yl)acetic acid (CAS 852400-33-0) is a high-purity analytical reference standard with the molecular formula C11H16N2O4 and a molecular weight of 240.26 g/mol.
The molecular framework of 2-(1-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]Decan-3-yl)acetic acid (C11H16N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(1-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]Decan-3-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- Methyl 2-(2,4-dioxo-1,3-diazaspiro[4.5]Decan-3-yl)acetate (CAS 1040330-96-8)
- 2-(2,4-Dioxo-1,3-diazaspiro[4.6]Undecan-3-yl)acetic acid (CAS 1094296-71-5)
- 1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]cyclobutane-1-carbonitrile (CAS 1909305-03-8)
- 3-(2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)propanoic acid (CAS 19282-94-1)
- (3-Methyl-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetic acid (CAS 869947-94-4)
- 2-(6-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetic acid (CAS 743441-93-2)
- 2-{8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}acetic acid (CAS 851170-87-1)
- 4-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid (CAS 853574-48-8)
Recommended Standards
- 1-Methyl-N-(pyridin-2-ylmethyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 869073-33-6)
- 2-(2,4-Diethoxy-6-methylpyrimidin-5-yl)acetic acid (CAS 500159-50-2)
- 1-Cyano-2-(isoquinolin-1(2H)-ylidene)ethyl acetate (CAS 56434-18-5)
- 2-(2-Methoxyphenyl)benzo[d]oxazol-5-amine (CAS 330974-57-7)
- 5-Amino-N,N-dimethylpentanamide oxalate (CAS 1221792-33-1)
- 1-(Chroman-6-yl)-N-methylmethanamine (CAS 950603-17-5)
- 1-amino-4-ethylcycloheptane-1-carboxylic acid (CAS 1468480-24-1)
- 2,2-Dimethylpropionic Acid (CAS 75-98-9)
- (Z)-N-(1-Bromo-1-(2-cyanophenyl)-3-oxo-3-(piperidin-1-yl)prop-1-en-2-yl)benzamide (CAS 1800044-59-0)
- 3-Trifluoromethoxy-piperidine Tosylate (CAS 2376143-20-1)
- Ethyl 5-amino-4-chloro-1-(2-ethoxyethyl)-1H-pyrazole-3-carboxylate (CAS 1427010-55-6)
- (3S,4S,5S)-3,4-dihydroxy-5-((1R,2R)-1,2,3-trihydroxypropyl)dihydrofuran-2(3H)-one (CAS 15397-07-6)
- (S)-2-Amino-4-(ethylamino)-4-oxobutanoic acid (CAS 7195-20-2)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
Why CATO?
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