4-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid CAS 853574-48-8
| CAS No. | 853574-48-8 |
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid.
CATO supplies 4-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid (CAS 853574-48-8), a certified reference material (molecular formula C11H16N2O4, MW 240.26 g/mol) for analytical method development and quality control.
The molecular framework of 4-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid (C11H16N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related dioxo Standards
- Methyl 2-(2,4-dioxo-1,3-diazaspiro[4.5]Decan-3-yl)acetate (CAS 1040330-96-8)
- 2-(2,4-Dioxo-1,3-diazaspiro[4.6]Undecan-3-yl)acetic acid (CAS 1094296-71-5)
- 1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]cyclobutane-1-carbonitrile (CAS 1909305-03-8)
- 3-(2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)propanoic acid (CAS 19282-94-1)
- (3-Methyl-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetic acid (CAS 869947-94-4)
- 2-(1-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]Decan-3-yl)acetic acid (CAS 852400-33-0)
- 2-(6-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetic acid (CAS 743441-93-2)
- 2-{8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}acetic acid (CAS 851170-87-1)
Recommended Standards
- 4,4'-(Hydrazine-1,2-diylidenebis(methanylylidene))diphenol (CAS 5466-23-9)
- 4-Amino-2-benzooxazol-2-yl-6-methyl-phenol (CAS 626218-32-4)
- 4,4'-(Ethane-1,2-diylidenebis(azanylylidene))diphenol (CAS 24764-93-0)
- 4-Amino-5-(2-fluorophenoxymethyl)-4h-1,2,4-triazole-3-thiol (CAS 733030-60-9)
- 2,2,2-Trifluoro-1-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)ethanone (CAS 261778-40-9)
- 5-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carboxamide (CAS 540740-77-0)
- (5Z)-5-[(5-Bromo-2-ethoxyphenyl)methylidene]-3-[(pyridin-3-yl)methyl]-2-sulfanylideneimidazolidin-4-one (CAS 320422-91-1)
- 6-Methoxy-2-phenyl-1h-1,3-benzodiazole (CAS 79877-53-5)
- (2E)-2-Methanesulfonyl-3-[6-(4-methylphenyl)imidazo[2,1-b][1,3]thiazol-5-yl]prop-2-enenitrile (CAS 691883-97-3)
- 2-Methylimidazo[1,2-a]pyridine-7-carboxylic Acid (CAS 1175928-10-5)
- 2-(prop-1-en-2-yl)benzaldehyde (CAS 23417-79-0)
- Ethyl 2-oxo-2-((3-(2-oxopyrrolidin-1-yl)phenyl)amino)acetate (CAS 1207012-65-4)
- 7-bromo-5-chloro-3-methyl-1-benzofuran-2-carboxylic acid (CAS 1019111-85-3)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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