| CAS No. | 852854-41-2 |
| Molecular Formula | C5H3BrF3NS |
| Molecular Weight | 246.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 246.05 g/mol gives 2-(Bromomethyl)-4-(trifluoromethyl)thiazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(Bromomethyl)-4-(trifluoromethyl)thiazole (CAS 852854-41-2), molecular formula C5H3BrF3NS and molecular weight 246.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Bromomethyl)-4-(trifluoromethyl)thiazole (C5H3BrF3NS) is characterized by a nitrile group, sulfur-containing functionality, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Bromomethyl)-4-(trifluoromethyl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C5H3BrF3NS |
| Molecular Weight | 246.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |