4-(Bromomethyl)-2-(trifluoromethyl)thiazole CAS 852854-38-7
| CAS No. | 852854-38-7 |
| Molecular Formula | C5H3BrF3NS |
| Molecular Weight | 246.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Bromomethyl)-2-(trifluoromethyl)thiazole (C5H3BrF3NS) is characterized by a nitrile group, sulfur-containing functionality, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 4-(Bromomethyl)-2-(trifluoromethyl)thiazole (CAS 852854-38-7), a certified reference material (molecular formula C5H3BrF3NS, MW 246.05 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3BrF3NS |
| Molecular Weight | 246.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromomethyl Standards
- 4-(Bromomethyl)-3-(difluoromethyl)benzonitrile (CAS 1261566-79-3)
- 2-(Bromomethyl)-6-(difluoromethyl)benzonitrile (CAS 1261819-57-1)
- 5-(Bromomethyl)-2-(trifluoromethyl)thiazole (CAS 157984-62-8)
- 2-(Bromomethyl)-4-(trifluoromethyl)thiazole (CAS 852854-41-2)
- 2-(Bromomethyl)-5-(trifluoromethyl)thiazole (CAS 2853613-10-0)
- 5-(Bromomethyl)-3-(trifluoromethyl)isothiazole (CAS 2853612-98-1)
- 1-(Bromomethyl)-3-methoxy-2-nitrobenzene (CAS 133486-62-1)
- 1-(Bromomethyl)-2-methoxy-3-nitrobenzene (CAS 180148-36-1)
Recommended Standards
- 3-Iodo-4-methylbenzaldehyde (CAS 58586-55-3)
- 4-Iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine (CAS 945600-09-9)
- 3-Iodo-2-methylbenzaldehyde (CAS 848444-83-7)
- 4-Iodobenzimidamide (CAS 229953-39-3)
- 1-Bromo-2-chloro-4-fluoro-3-(fluoromethyl)benzene (CAS 2244083-98-3)
- 5,6-Dibromo-2,1,3-benzothiadiazole (CAS 18392-81-9)
- 5-Phenyl-1,3,4-thiadiazol-2-amine sulfate (CAS 340169-03-1)
- 2-((1H-Pyrazol-1-yl)methyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine (CAS 1422069-37-1)
- (1R,5S)-7-(Trifluoromethyl)-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine (CAS 357425-02-6)
- 4'-Hexyl-[1,1'-biphenyl]-4-carbonitrile (CAS 41122-70-7)
- 2,6-Difluoro-N-methylaniline (CAS 55847-14-8)
- Triptycenetris(1,2,5-selenadiazole) (CAS 2771312-95-7)
- Methyl 2-(benzyloxy)-5-methoxy-3-nitrobenzoate (CAS 1221792-98-8)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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