3-(5-(4-Chlorophenyl)furan-2-yl)-N-(2-fluorophenyl)propanamide CAS 853311-67-8
| CAS No. | 853311-67-8 |
| Molecular Formula | C19H15ClFNO2 |
| Molecular Weight | 343.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(5-(4-Chlorophenyl)furan-2-yl)-N-(2-fluorophenyl)propanamide (C19H15ClFNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-(5-(4-Chlorophenyl)furan-2-yl)-N-(2-fluorophenyl)propanamide (CAS 853311-67-8), molecular formula C19H15ClFNO2 and molecular weight 343.78 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H15ClFNO2 |
| Molecular Weight | 343.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 3-(5-(3-Chlorophenyl)furan-2-yl)-N-(2-fluorophenyl)propanamide (CAS 853312-65-9)
- 3-(5-(3-Chlorophenyl)furan-2-yl)-N-(4-fluorophenyl)propanamide (CAS 853312-69-3)
- 3-(5-(4-Chlorophenyl)furan-2-yl)-N-(4-fluorophenyl)propanamide (CAS 853311-61-2)
- 6-(2-Chlorophenyl)-2-(methylthio)imidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one (CAS 1395026-26-2)
- 2-(3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl)-N-(4-methoxyphenyl)acetamide (CAS 478042-39-6)
- 2-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)acetamide (CAS 478042-37-4)
- 3-(2-Chlorophenyl)-N-(6-methoxypyridin-3-yl)-5-methylisoxazole-4-carboxamide (CAS 497060-39-6)
- Methyl 4-((3-(4-chlorophenyl)isoxazol-5-yl)methoxy)benzoate (CAS 478066-49-8)
Recommended Standards
- Ethyl (E)-3-(6-((tert-butoxycarbonyl)amino)-3-chloro-2-fluorophenyl)acrylate (CAS 2620742-85-8)
- 2-Methoxyethyl (5-(chlorosulfonyl)naphthalen-1-yl)carbamate (CAS 728864-82-2)
- N-[(E)-3-(4-chlorophenyl)-2-(4-fluorophenyl)prop-2-enoyl]-2-methyl-prop-2-enamide (CAS 2241020-49-3)
- 1-(3-Chlorobenzyl)-3-(4-fluorobenzyl)-4-hydroxypyridin-2(1H)-one (CAS 477856-05-6)
- 1-Bromo-2-naphthonitrile (CAS 20176-08-3)
- 4-Methyl-3-(thiophen-3-yl)-1h-pyrazol-5-amine (CAS 1312443-95-0)
- N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)acetamide (CAS 1443367-96-1)
- Bromfenac Impurity 74 (CAS 748735-66-2)
- 5-(Chloromethyl)-n,n-dimethylthiophene-2-sulfonamide (CAS 1486675-03-9)
- (+)-trans-Chlordane (CAS 66514-87-2)
- tert-Butyl 2-(tert-butyl)aziridine-1-carboxylate (CAS 1956370-20-9)
- Dioxopromethazine Hydrochloride (CAS 15374-15-9)
- (3-Amino-6-chloro-2-fluorophenyl)boronic acid (CAS 2413458-87-2)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com