N-(3-Chloro-2-methylphenyl)-5-(2-chlorophenyl)furan-2-carboxamide CAS 853314-72-4

Purity 97%+In StockPharmaceutical Standards
CAS No.853314-72-4
Molecular FormulaC18H13Cl2NO2
Molecular Weight346.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3-Chloro-2-methylphenyl)-5-(2-chlorophenyl)furan-2-carboxamide CAS 853314-72-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 346.21 g/mol gives N-(3-Chloro-2-methylphenyl)-5-(2-chlorophenyl)furan-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(3-Chloro-2-methylphenyl)-5-(2-chlorophenyl)furan-2-carboxamide (CAS 853314-72-4) is a high-purity analytical reference standard with the molecular formula C18H13Cl2NO2 and a molecular weight of 346.21 g/mol.

The molecular framework of N-(3-Chloro-2-methylphenyl)-5-(2-chlorophenyl)furan-2-carboxamide (C18H13Cl2NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(3-Chloro-2-methylphenyl)-5-(2-chlorophenyl)furan-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H13Cl2NO2
Molecular Weight346.21 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms1

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