3-(5-(2-Chlorophenyl)furan-2-yl)-N-(4-fluorophenyl)acrylamide CAS 853348-41-1
| CAS No. | 853348-41-1 |
| Molecular Formula | C19H13ClFNO2 |
| Molecular Weight | 341.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(5-(2-Chlorophenyl)furan-2-yl)-N-(4-fluorophenyl)acrylamide.
CATO supplies 3-(5-(2-Chlorophenyl)furan-2-yl)-N-(4-fluorophenyl)acrylamide (CAS 853348-41-1), a certified reference material (molecular formula C19H13ClFNO2, MW 341.76 g/mol) for analytical method development and quality control.
The molecular framework of 3-(5-(2-Chlorophenyl)furan-2-yl)-N-(4-fluorophenyl)acrylamide (C19H13ClFNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H13ClFNO2 |
| Molecular Weight | 341.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 3-((4-Chlorophenyl)(2-(trifluoromethyl)phenyl)methoxy)azetidine (CAS 791848-72-1)
- 3-(5-(2-Chlorophenyl)furan-2-yl)-N-(2-fluorophenyl)acrylamide (CAS 853348-40-0)
- (2-Chlorophenyl)(3-(3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)azetidin-1-yl)methanone (CAS 1323707-27-2)
- 4-(2-(2-(2-Chlorophenyl)-5-methyloxazol-4-yl)ethoxy)benzaldehyde (CAS 103789-58-8)
- 1306753-59-2 1-{2-(4-Chlorophenyl)-7-[(E)-2-(dimethylamino)vinyl][1,2,4]triazolo[1,5-a]pyrimidin-6-yl}ethanone MFCD19103624 (CAS 1306753-59-2)
- 2-(4-Chlorophenyl)-N-(3-phenylpropyl)-2H-tetrazole-5-carboxamide (CAS 1396792-10-1)
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Recommended Standards
- 4-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-sulfonyl chloride (CAS 568577-83-3)
- 4-Chloro-3-[(4-methoxyphenyl)sulfamoyl]benzoic acid (CAS 109029-99-4)
- Methyl 4-chloro-6-(4'-fluoro-[1,1'-biphenyl]-4-yl)picolinate (CAS 1367127-90-9)
- Methyl 2-(benzyloxy)-6-(chlorosulfonyl)isonicotinate (CAS 1393531-28-6)
- Allyl piperidin-4-ylcarbamate hydrochloride (CAS 885274-96-4)
- 1-(Cyclopropylmethyl)-1H-imidazol-4-amine (CAS 1260879-14-8)
- Effinaconazole Methylene Methanone Impurity (CAS 188904-84-9)
- N-((1-Benzylpyrrolidin-2-yl)methyl)-2-chloroacetamide (CAS 1353963-57-1)
- Methyl L-lysinate (CAS 687-64-9)
- 3-Amino-4-(4-chlorophenyl)-1-ethylazetidin-2-one (CAS 1706532-42-4)
- 2-(2-(Trifluoromethyl)phenyl)acetohydrazide (CAS 428507-91-9)
- 4-Chloro-N-(3-(pyrrolidin-1-yl)propyl)aniline (CAS 1226259-88-6)
- N-Cyclopropyl-N-(piperidin-2-ylmethyl)acetamide (CAS 1353943-69-7)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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