4-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-sulfonyl chloride CAS 568577-83-3

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-sulfonyl chloride (CAS 568577-83-3), molecular formula C11H7ClF3NO2S2 and molecular weight 341.76 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-sulfonyl chloride (C11H7ClF3NO2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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