Rivastigmine EP Impurity C CAS 855300-09-3
| CAS No. | 855300-09-3 |
| Molecular Formula | C12H15NO3 |
| Molecular Weight | 221.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Rivastigmine EP Impurity C (CAS 855300-09-3), a pharmacopoeial impurity reference standard (molecular formula C12H15NO3, MW 221.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Rivastigmine EP Impurity C (C12H15NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 221.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15NO3 |
| Molecular Weight | 221.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Rivastigmine Standards
- Rivastigmine Impurity 14 (CAS 1346242-31-6)
- Rivastigmine Impurity 19 (CAS CATO-C4X-138419)
- Rivastigmine USP Related Compound B (CAS 25081-93-0)
- Rivastigmine EP Impurity B (CAS 1230021-28-9)
- Rivastigmine EP Impurity E (CAS 923035-05-6)
- Rivastigmine RC 5 (CAS 1070660-34-2)
- Rivastigmine USP Related Compound F (CAS 1346602-84-3)
- Rivastigmine Impurity 11 (CAS 123441-03-2)
Recommended Standards
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- Finerenone Impurity 101 (CAS CATO-C4X-2880101)
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- 1-[2-(2-Trifluoromethyl-phenyl)-thiazol-4-yl]-ethanone (CAS 1469150-14-8)
- N-[(4-Chlorophenyl)methyl]-2-{[3-methyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1040683-26-8)
- 2-(4'-Bromo-biphenyl-4-yl)-1,2-dihydronaphthalene (CAS 861212-65-9)
- Cefoxitin Impurity 39 (CAS CATO-C4X-157839)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
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