2-Bromo-4-(trifluoromethyl)benzoyl chloride CAS 85663-09-8
| CAS No. | 85663-09-8 |
| Molecular Formula | C8H3BrClF3O |
| Molecular Weight | 287.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromo-4-(trifluoromethyl)benzoyl chloride (C8H3BrClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Bromo-4-(trifluoromethyl)benzoyl chloride (CAS 85663-09-8), a certified reference material (molecular formula C8H3BrClF3O, MW 287.46 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-4-(trifluoromethyl)benzoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H3BrClF3O |
| Molecular Weight | 287.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 1-(2-Bromo-4-chlorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1033805-23-0)
- 1-(2-Bromo-5-chlorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1033805-74-1)
- 4-Bromo-2-(trifluoromethyl)benzoyl Chloride (CAS 104356-17-4)
- 2-Bromo-3-(trifluoromethyl)benzoyl chloride (CAS 1214376-97-2)
- 4-Bromo-2-chloro-5-(trifluoromethyl)benzaldehyde (CAS 1414870-64-6)
- 2-Bromo-6-chloro-4-(trifluoromethyl)benzaldehyde (CAS 1415130-43-6)
- 1-(4-bromo-2-chlorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1715018-78-2)
- 1-(4-Bromo-3-chlorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1824056-50-9)
Recommended Standards
- 1-(2-Bromo-6-chlorophenyl)-2,2,2-trifluoroethan-1-one (CAS 886502-80-3)
- 2-Bromo-5-(trifluoromethyl)benzoyl chloride (CAS 944836-48-0)
- 2-Chloro-3-fluoro-4-iodo-5-methoxypyridine (CAS 2769929-62-4)
- 2-Undecylthiazolidine-4-carboxylic acid (CAS 298186-80-8)
- 2-(2-Chloro-6-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1805273-23-7)
- 6-Amino-2-(chloromethyl)-5-(difluoromethyl)nicotinic acid (CAS 1806839-65-5)
- (5-((4-Chlorophenyl)thio)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methanol (CAS 318247-53-9)
- 3-(4-Methylbenzamido)thiophene-2-carboxylic acid (CAS 478080-03-4)
- 4-Chloro-1,6-dimethylpyridin-2(1H)-one (CAS 5658-86-6)
- 6-(Trifluoromethyl)quinolin-8-ol (CAS 321-70-0)
- 1-(5-Methylthiazol-2-yl)-1H-pyrrole-2-carbaldehyde (CAS 383136-04-7)
- 1,4-Dichloro-2,2-difluorobutane (CAS 381-34-0)
- 3-{[(2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl)amino]methyl}benzonitrile (CAS 1038223-14-1)
- Mitogenic Pentapeptide (CAS 87173-03-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com