Promethazine Impurity 39 CAS 857523-80-9
| CAS No. | 857523-80-9 |
| Molecular Formula | C17H22N2 |
| Molecular Weight | 254.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 254.37 g/mol gives Promethazine Impurity 39 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Promethazine Impurity 39 (CAS 857523-80-9) is a certified pharmaceutical impurity reference standard with the molecular formula C17H22N2 and a molecular weight of 254.37 g/mol.
Promethazine Impurity 39 (C17H22N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Promethazine Impurity 39 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H22N2 |
| Molecular Weight | 254.37 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Promethazine Standards
- Promethazine Impurity 53 (CAS CATO-C4X-141853)
- Promethazine Impurity 2 (CAS 1217-37-4)
- Promethazine impurity 59 (CAS CATO-C4X-141859)
- Promethazine impurity 58 (CAS CATO-C4X-141858)
- Promethazine Impurity 7 (CAS 15375-48-1)
- Promethazine Impurity 29 (CAS 20962-92-9)
- Promethazine EP Impurity C (R-Isomer) (CAS CATO-C3D-262692)
- Promethazine EP Impurity C (CAS 37707-23-6)
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