2-amino-8-(3-chlorophenyl)-6,9-dihydro-1H-purin-6-one CAS 857524-98-2
| CAS No. | 857524-98-2 |
| Molecular Formula | C11H8ClN5O |
| Molecular Weight | 261.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-amino-8-(3-chlorophenyl)-6,9-dihydro-1H-purin-6-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-amino-8-(3-chlorophenyl)-6,9-dihydro-1H-purin-6-one (CAS 857524-98-2), molecular formula C11H8ClN5O and molecular weight 261.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-amino-8-(3-chlorophenyl)-6,9-dihydro-1H-purin-6-one (C11H8ClN5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-amino-8-(3-chlorophenyl)-6,9-dihydro-1H-purin-6-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN5O |
| Molecular Weight | 261.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related amino Standards
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- 3-[(1Z)-2-Amino-1,2-dicyanoeth-1-en-1-yl]-1-(4-chlorophenyl)urea (CAS 865658-74-8)
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Recommended Standards
- 2-(3-((1H-1,2,4-triazol-1-yl)methyl)-1H-1,2,4-triazol-1-yl)-6-chloropyridine (CAS 477852-44-1)
- 1-(4-Chlorophenyl)-4-(1H-1,2,4-triazol-1-yl)-1H-pyrazol-5-ol (CAS 477712-95-1)
- 1-(3-Chlorophenyl)-4-(1H-1,2,4-triazol-1-yl)-1H-pyrazol-5-ol (CAS 477762-18-8)
- 4-Chloro-1-(6-methoxypyridin-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 650637-96-0)
- 2-Amino-N-(2-methoxyphenyl)acetamide hydrochloride (CAS 164979-82-2)
- 3,6-Difluoro-2-hydroxybenzoic acid (CAS 749230-37-3)
- 2-Amino-4-(trifluoromethyl)phenol (CAS 454-81-9)
- (1R)-1-(2-anthryl)-2-methoxyethylamine (CAS 1270080-14-2)
- 2-(Methoxymethyl)pyrrolidine hydrochloride (CAS 1376123-33-9)
- (S)-3-Fluoropiperidine (CAS 871791-81-0)
- H-D-His(3-Me)-OH (CAS 163750-76-3)
- 2-Chloro-N-(2,3-dichlorobenzyl)-N-ethylacetamide (CAS 1353963-61-7)
- 5-(3-Fluorophenyl)-1H-indole (CAS 893739-63-4)
- Angiotensin II Antipeptide (CAS 121379-63-3)
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