5-(Chloromethyl)-3-(4-fluoro-2-(trifluoromethyl)phenyl)isoxazole CAS 858939-35-2
| CAS No. | 858939-35-2 |
| Molecular Formula | C11H6ClF4NO |
| Molecular Weight | 279.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Chloromethyl)-3-(4-fluoro-2-(trifluoromethyl)phenyl)isoxazole.
5-(Chloromethyl)-3-(4-fluoro-2-(trifluoromethyl)phenyl)isoxazole (CAS 858939-35-2), molecular formula C11H6ClF4NO and molecular weight 279.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-(Chloromethyl)-3-(4-fluoro-2-(trifluoromethyl)phenyl)isoxazole is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 279.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(Chloromethyl)-3-(4-fluoro-2-(trifluoromethyl)phenyl)isoxazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6ClF4NO |
| Molecular Weight | 279.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 4-[2-(Chloromethyl)-4-(trifluoromethyl)phenyl]morpholine (CAS 892502-15-7)
- 3-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)-N-ethyl-N-methylbenzamide (CAS 1119449-61-4)
- 3-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-N-isopropylbenzamide (CAS 1119452-67-3)
- 6-(Chloromethyl)-N2-(4-ethoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 105704-31-2)
- 6-(Chloromethyl)-N2-(2-ethoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 1379811-41-2)
- 6-(Chloromethyl)-N2-(2-methoxy-5-methylphenyl)-1,3,5-triazine-2,4-diamine (CAS 1379811-75-2)
- 2-(3-(Chloromethyl)-6-methoxypyridin-2-yl)ethyl methanesulfonate (CAS 1003589-87-4)
- (2-(Chloromethyl)-4-nitrophenyl)(phenyl)sulfane (CAS 52548-34-2)
Recommended Standards
- 3-(4-Chloro-2-fluoro-5-methylphenyl)-5-(trifluoromethyl)isoxazole (CAS 653569-92-7)
- 8-Chloro-5-fluoro-4-methoxy-2-(trifluoromethyl)quinoline (CAS 917251-95-7)
- Ethyltris(dimethylsiloxy)silane (CAS 150320-87-9)
- 3-Chloro-5-fluoro-7-nitro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1437458-04-2)
- 1-(3-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-amine,HCl (CAS 1431966-80-1)
- 2-(3-Hydroxypyrrolidin-1-yl)-N-(4-methylthiazol-2-yl)acetamide (CAS 1496417-79-8)
- N-(5-Cyclopropoxy-2-nitropyridin-3-yl)methanesulfonamide (CAS 1243450-00-1)
- (3Z)-4-[(4-Acetylphenyl)amino]-3-(3,4-dimethoxyphenyl)but-3-en-2-one (CAS 339017-47-9)
- 4-Bromo-N-(3-fluoro-4-methylphenyl)benzamide (CAS 1003237-68-0)
- 1-(3-(Isopropylamino)pyrrolidin-1-yl)ethan-1-one (CAS 1353973-46-2)
- 2-((1-(Ethoxycarbonyl)piperidin-4-yl)oxy)acetic acid (CAS 1344046-33-8)
- (4-(4-Methoxyphenyl)pyrrolidin-3-yl)methanol (CAS 937692-64-3)
- tert-Butyl 4-((4-methylpyrimidin-2-yl)amino)piperidine-1-carboxylate (CAS 1261232-51-2)
- D-[Val]10-Semaglutide (CAS CATO-CPTD788630)
Why CATO?
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