2-((3-Cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide CAS 626222-12-6
| CAS No. | 626222-12-6 |
| Molecular Formula | C19H16F3N3O2S |
| Molecular Weight | 407.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 407.41 g/mol gives 2-((3-Cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-((3-Cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 626222-12-6), a certified reference material (molecular formula C19H16F3N3O2S, MW 407.41 g/mol) for analytical method development and quality control.
2-((3-Cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide (C19H16F3N3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16F3N3O2S |
| Molecular Weight | 407.41 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- 2-((6-Benzyl-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N,N-diethylacetamide (CAS 723748-27-4)
- 2-{[3-cyano-6-ethyl-5-methyl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(1-phenylethyl)acetamide (CAS 664999-19-3)
- 2-Cyano-N-cyclohexyl-3-(2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide (CAS 477734-60-4)
- 2-[(1Z)-1-Cyano-2-phenyleth-1-en-1-yl]-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 338786-53-1)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 924236-36-2)
- 2-Cyano Loratadine (CAS 860010-31-7)
- 4-Cyano Loratadine (CAS 860010-33-9)
- 4-Cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide 4406AC 885704-21-2 C23H30N6O (CAS 885704-21-2)
Recommended Standards
- (3S,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone (CAS 1478664-17-3)
- 2-((4-Ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 618414-71-4)
- Riociguat Impurity 41 (CAS CATO-C4X-174941)
- 2-Methoxyethyl 2-amino-4-(3,4-difluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (CAS 445382-17-2)
- 2-[(4-Methoxybenzyl)amino]nicotinonitrile (CAS 854382-10-8)
- 1,4-Dipiperazino-2,3,5,6-tetrafluorobenzene (CAS 502616-02-6)
- 2-Methyl-1-[(3-nitrophenyl)methyl]piperazine (CAS 1240573-25-4)
- 1-(5-bromopyridin-2-yl)piperazine dihydrochloride (CAS 1170221-91-6)
- 2-(3-Chlorophenyl)-2,2-difluoroacetamide (CAS 780769-48-4)
- 1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-((4-chlorophenyl)thio)propan-1-one (CAS 634155-05-8)
- Tert-butyl 4-((3-nitrobenzyl)amino)piperidine-1-carboxylate (CAS 1233952-99-2)
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