8-Methoxy-2,4-dimethylquinazoline CAS 860192-54-7
| CAS No. | 860192-54-7 |
| Molecular Formula | C11H12N2O |
| Molecular Weight | 188.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Methoxy-2,4-dimethylquinazoline (C11H12N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
8-Methoxy-2,4-dimethylquinazoline (CAS 860192-54-7), molecular formula C11H12N2O and molecular weight 188.23 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12N2O |
| Molecular Weight | 188.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 2-Methoxy-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 100060-08-0)
- 3-Methoxy-5-methyl-1-phenyl-1H-pyrazole (CAS 1013-38-3)
- 6-Methoxy-2-methylquinolin-4-amine, 97% (CAS 104217-23-4)
- 6-Methoxy-2-methylquinolin-5-amine (CAS 114656-78-9)
- 1-Benzyl-4-methoxy-1H-pyrazole (CAS 1218994-43-4)
- 8-Methoxy-4-methylquinolin-2-amine (CAS 1307239-63-9)
- 8-Methoxy-6-methylquinolin-4-amine (CAS 1315344-56-9)
- 2-methoxy-6-(1H-pyrrol-1-ylmethyl)pyridine (CAS 1341376-97-3)
Recommended Standards
- 8-Ethoxyquinolin-5-amine (CAS 75793-53-2)
- 8-Methoxy-5-methylquinolin-3-amine (CAS 2090264-78-9)
- 8-Ethoxyquinolin-2-amine (CAS 635755-43-0)
- Acetaldehyde O-(1-methyl-1H-indol-3-yl) oxime (CAS 52971-32-1)
- N-(7-Chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-2-yl)-N-methyl- acetamide (CAS 7563-73-7)
- Ethyl 5-formyl-4-methyl-1H-pyrrole-3-carboxylate (CAS 6339-66-8)
- 3-(Cyanomethyl)benzenesulfonamide (CAS 52320-62-4)
- 4-fluoro-4-[4-(trifluoromethyl)phenyl]piperidine hydrochloride (CAS 1004619-25-3)
- 6-Ethyl-4-methoxyquinoline-2-carboxylic acid (CAS 1355196-14-3)
- N3-(3-Ethoxypropyl)-1-ethyl-1H-pyrazole-3,4-diamine dihydrochloride (CAS 1431968-07-8)
- Copper(II) (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (CAS 70581-71-4)
- 4-((3,4-Dihydroxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 577789-70-9)
- 3-Nitro-4-propyl-1H-pyrrole-2-carboxylic acid (CAS 866043-56-3)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
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