2-((4-(3-Chlorophenyl)piperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(1H)-one CAS 860649-48-5
| CAS No. | 860649-48-5 |
| Molecular Formula | C21H22ClN5O |
| Molecular Weight | 395.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-((4-(3-Chlorophenyl)piperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(1H)-one (C21H22ClN5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-((4-(3-Chlorophenyl)piperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(1H)-one (CAS 860649-48-5), molecular formula C21H22ClN5O and molecular weight 395.89 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((4-(3-Chlorophenyl)piperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22ClN5O |
| Molecular Weight | 395.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)-1-{4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]piperidin-1-yl}ethan-1-one (CAS 1775303-17-7)
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Recommended Standards
- (1-(3-Chloro-4-methylphenyl)-1H-1,2,3-triazol-4-yl)(4-(4-methylpiperazin-1-yl)phenyl)methanone (CAS 477847-90-8)
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