2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-one CAS 860650-06-2
| CAS No. | 860650-06-2 |
| Molecular Formula | C16H10ClF2NO |
| Molecular Weight | 305.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-one (CAS 860650-06-2), molecular formula C16H10ClF2NO and molecular weight 305.71 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-one (C16H10ClF2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 305.71 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF2NO |
| Molecular Weight | 305.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 1365962-37-3 5-{[Chloro(phenyl)acetyl]amino}-2-hydroxybenzoic acid MFCD22056617 (CAS 1365962-37-3)
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Recommended Standards
- 2-[2-(4-chlorophenoxy)acetamido]benzoic acid (CAS 69764-09-6)
- 2-Chloro-5-nitrobenzyl 4-methylbenzoate (CAS 331459-97-3)
- 2-[2-(3-chlorophenoxy)acetamido]benzoic acid (CAS 782480-99-3)
- 3-(3-Chlorophenyl)-2-(4-nitrophenyl)propanoic acid (CAS 860610-54-4)
- 1-(1,8-Dihydroxynaphthalen-2-yl)ethanone (CAS 833-27-2)
- 1-(4-Methyl-3,4-dihydroquinoxalin-1(2H)-yl)ethanone (CAS 669695-07-2)
- 7-Methyl-1H-indol-5-amine (CAS 90868-09-0)
- 1-(3,4-Dihydro-2h-chromen-3-yl)methanamine Hydrochloride (CAS 113771-75-8)
- 4-Oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (CAS 358732-55-5)
- 4-(2-((4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamido)benzamide (CAS 618426-84-9)
- (2R,4S)-2-((1H-Indol-3-yl)methyl)-4-amino-2-hydroxypentanedioic acid (CAS 400769-79-1)
- N-(4-(2-bromoacetyl)-3-chlorophenyl)methanesulfonamide (CAS 2001565-28-0)
- 3-Bromo-4-(N-morpholino)phenol (CAS 1171917-57-9)
- Semaglutide impurity 68 (CAS CATO-C4X-222668)
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