2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-ol CAS 860650-07-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-ol.

2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-ol (CAS 860650-07-3), molecular formula C16H12ClF2NO and molecular weight 307.72 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-ol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 307.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-2,2-difluoro-1-(2-phenyl-1H-indol-3-yl)ethan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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