2-Chloro-1-methyl-5-nitro-1H-imidazole CAS 86072-07-3
| CAS No. | 86072-07-3 |
| Molecular Formula | C4H4ClN3O2 |
| Molecular Weight | 161.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-1-methyl-5-nitro-1H-imidazole (CAS 86072-07-3), molecular formula C4H4ClN3O2 and molecular weight 161.55 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-1-methyl-5-nitro-1H-imidazole (C4H4ClN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H4ClN3O2 |
| Molecular Weight | 161.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1428577-87-0 5-Chloro-1-(~2~H_3_)methyl-4-nitro-1H-pyrazole DTXSID40857353 (CAS 1428577-87-0)
- 2-Chloro-1-methyl-4-nitro-1H-imidazole (CAS 63634-21-9)
- 2-chloro-N-(1H-1,2,3,4-tetrazol-5-yl)acetamide (CAS 6158-78-7)
- 3-Chloro-1-methyl-4-nitro-1H-pyrazole (CAS 299930-70-4)
- 4-Chloro-1-methyl-2-nitro-1H-imidazole (CAS 63634-20-8)
- 4-chloro-1-methyl-5-nitro-1H-pyrazole (CAS 84547-95-5)
- 4-Chloro-2-methyl-5-nitro-1H-imidazole (CAS 63662-67-9)
- 4-Chloro-3-methyl-5-nitro-1H-pyrazole (CAS 400753-12-0)
Recommended Standards
- 1-(Chloromethyl)-4-nitro-1h-pyrazole (CAS 51355-88-5)
- 3-(Chloromethyl)-1,2,4-oxadiazole-5-carboxamide (CAS 25977-21-3)
- 1-Amino-5-chlorouracil (CAS 127984-94-5)
- 1-(Chloromethyl)-3-nitro-1H-pyrazole (CAS 102388-00-1)
- 1-Bromo-2-ethoxy-3-vinylbenzene (CAS 2168980-71-8)
- N,N,5'-trimethyl-3,4,5,6-tetrahydro-[2,3'-bipyridin]-6'-amine (CAS 1352523-39-7)
- Pyridine-d<SUB>5</SUB> <I>N</I>-oxide (CAS 19639-76-0)
- 2-(1-Chlorobutyl)-5-propylfuran (CAS 96212-20-3)
- Pomolic acid β-D-glucopyranosyl ester (CAS 83725-24-0)
- 7-(2-(Oxiran-2-yl)ethoxy)-2H-chromen-2-one (CAS 381689-75-4)
- (2'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methanamine (CAS 472964-38-8)
- tert-Butyl 3-nitrobenzoate (CAS 58656-99-8)
- N-(phenylmethyl)-Guanidine acetate (1:1) (CAS 117053-38-0)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com