8-(4-Chlorophenyl)-6-methyl-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile CAS 860784-22-1

Purity 97%+In StockPharmaceutical Standards
CAS No.860784-22-1
Molecular FormulaC18H16ClN3
Molecular Weight309.79 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-(4-Chlorophenyl)-6-methyl-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile CAS 860784-22-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-(4-Chlorophenyl)-6-methyl-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile.

8-(4-Chlorophenyl)-6-methyl-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile (CAS 860784-22-1) is a high-purity analytical reference standard with the molecular formula C18H16ClN3 and a molecular weight of 309.79 g/mol.

8-(4-Chlorophenyl)-6-methyl-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile (C18H16ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 8-(4-Chlorophenyl)-6-methyl-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H16ClN3
Molecular Weight309.79 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms3

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