| CAS No. | 861207-86-5 |
| Molecular Formula | C19H12F3N5O |
| Molecular Weight | 383.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (1-(4-Methyl-6-(trifluoromethyl)pyrimidin-2-yl)-1H-1,2,3-triazol-4-yl)(naphthalen-2-yl)methanone (CAS 861207-86-5), a certified reference material (molecular formula C19H12F3N5O, MW 383.33 g/mol) for analytical method development and quality control.
The molecular framework of (1-(4-Methyl-6-(trifluoromethyl)pyrimidin-2-yl)-1H-1,2,3-triazol-4-yl)(naphthalen-2-yl)methanone (C19H12F3N5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C19H12F3N5O |
| Molecular Weight | 383.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |